Glioblastoma NOS and callosal dygenesis
Confusion. Prior cranial surgery.
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There is evidence of prior surgery. Left high frontal irregular space occupying lesion is seen eliciting low T1 and high T2/FLAIR signal with areas of high T1 and low T2/FLAIR signals (indicating met-Hb) and peripheral irregular contrast enhancement. The lesion exerts mass effect and is seen surrounded by vasogenic edema. MR spectroscopy shows marked elevation of the choline with depression of the normal markers (N-acetyle aspartate and creatine) as well as small lipid / lactate doublet, with similar changes seen in the edema around the lesion.
Complete agenesis of the corpus callosum.
Pathologically proven high-grade glioma; glioblastoma (WHO grade IV), and complete agenesis of the corpus callosum.