MRI Brain (selected images)
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The MRI revealed an extensive infiltrating glioma with the expansion of the posterior body and splenium of the corpus callosum, involving both medial parietal lobes. The right side is more extensive infiltrating around the lateral ventricle to involve the thalamus, parieto-temporal deep white matter. The left side of the tumour extended into the left medial parietal deep white matter, with a focal area of irregular enhancement and central necrosis, this being suggestive of a high-grade necrotic component.
A second MRI (8 days apart) was suggestive of a very extensive infiltrating glioma or gliomatosis cerebri. With areas of high grade transformation that seem to be progressing very rapidly (new areas of necrosis and enhancement developing in the callosal components, as well as other new areas of restricted diffusivity suggesting higher grade transformation but in the pre-necrotic stage).