Gliosarcoma

Case contributed by A.Prof Frank Gaillard
Modality: MRI

See below

Modality: MRI

heterogenously, but mainly peripherally, enhancing lesion in the parietal lobe, with extensive surrounding edema and positive mass effect. 

Case Discussion

Final Diagnosis: 

Brain, left parietal: Astrocytoma grade 4/4 using the Daumas-Duport grading system (glioblastoma multiforme) with spindle component - gliosarcoma.

Microscopic Description:

Sections show a glial tumour displaying necrosis, vascular proliferation, a spindle cell component (consistent with so-called gliosarcoma), and obvious mitotic activity. The tumour cells display features that range from small cell to gemistocytic characteristics. Blood vessels appear somewhat hyalinized in areas.

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Case Information

rID: 5322
Case created: 2nd Jan 2009
Last edited: 23rd Sep 2015
Inclusion in quiz mode: Included

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