Case contributed by A.Prof Frank Gaillard

Patient Data

Age: Adult

Heterogeneously, but mainly peripherally, enhancing lesion in the parietal lobe, with extensive surrounding edema and positive mass effect. Spectroscopy demonstrates elevated choline and depressed NAA. Elevation of rCBV (area under the curve) is seen in the solid component. 

Case Discussion

The patient went on to have a resection. 


Microscopic Description:

Sections show a glial tumor displaying necrosis, vascular proliferation, a spindle cell component (consistent with so-called gliosarcoma), and obvious mitotic activity. The tumor cells display features that range from small cell to gemistocytic characteristics. Blood vessels appear somewhat hyalinized in areas.

Final Diagnosis: gliosarcoma.

Note: This case predates the recent (2016) revision WHO classification of CNS tumors and IDH status is not available. 

PlayAdd to Share

Case information

rID: 5322
Published: 2nd Jan 2009
Last edited: 21st May 2017
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.