Graft versus host disease in lung transplant patient for cystic fibrosis
Diagnosis probable
Presentation
Status post lung transplant. Abdominal pain.
Patient Data
Age: 30 years
Gender: Female
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- diffuse intestinal mural thickening and mucosal enhancement
- dilated fluid-filled loops of small bowel and colon
- complete fatty replacement of pancreatic parenchyma (history of cystic fibrosis)
- mature teratoma of right ovary, with fatty attenuation, and teeth
- L2 vertebral body hemangioma
Case Discussion
Graft vs host disease
- the allogeneic lung transplant's T cells attack the histo-incompatible, immunocompromised host
- severe intestinal inflammation, abdominal pain, diarrhea
- sloughed mucosa may cause enhancing granulation tissue, in dilated fluid-filled bowel loops
Cystic fibrosis
- total fatty replacement of the pancreatic parenchyma, due to exocrine disease.
- pulmonary disease, necessitated the lung transplant in this patient
Ovarian teratoma (incidental finding)
- benign well differentiated congenital tumor, with ectodermal, endodermal and/or mesodermal elements
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