Granular cell tumor of the breast

Case contributed by Dr Ali Alsmair


The patient presented with mass feeling in the right breast.

Patient Data

Age: 50 years
Gender: Female

Evidence of an ill defined speculated lesion seen in the upper part of the right breast, seen on MLO projection only. No skin thickening or nipple retraction.


The lesion appeared as a speculated lesion with internal vascularity and marked acoustic shadowing. It appears completely solid on elastography. No architectural distortion.

The lesion appears speculated and located in the upper inner quadrant of the right breast. No skin thickening or retraction.

The lesion was biopsied and this is the histopathology report, confirming the diagnosis of granular cell tumor of the breast.

Case Discussion

The granular cell tumor of the breast is an uncommon, usually benign tumor which is possibly of neural origin.

On mammography, these tumors can present as an ill-defined or speculated lesions, similar to breast carcinoma.

On ultrasound, this tumor mostly appears as a solid, hypoechoic, ill-defined mass, associated with a posterior shadowing, or as a well-circumscribed oval mass, associated with a posterior enhancement, depending on the extent of infiltration and degree of reactive fibrosis.

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