Granulomatosis with polyangiitis

Case contributed by Dr Abdallah Al Khateeb


Worsening kidney function. Recent onset hemoptysis on a background of chronic cough. Longstanding paranasal sinus disease.

Patient Data

Age: 32 years old
Gender: Female

Sinuses CT

Bilateral mucosal thickening with bony thinning. Perforation of the nasal septum is also seen.


Chest CT

Few randomly scattered lung nodules are seen bilaterally, some show cavitary change with thick walls.

Case Discussion

The lung nodules seen in this case can be due to septic emboli, metastasis or vasculitis. The fact that the patient also has upper respiratory tract involvement, a positive c-ANCA lab result and probable renal system involvement, makes vasculitis in the form of Wegener granulomatosis the more likely diagnosis.

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Case information

rID: 43324
Published: 4th Mar 2016
Last edited: 14th Jan 2020
System: Chest
Inclusion in quiz mode: Included

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