Granulomatosis with polyangitis - pulmonary cavities

Case contributed by Dr Bruno Di Muzio


Cough and fever. Recurrence of symptoms three months after her last hospitalisation.

Patient Data

Age: 34-year-old
Gender: Female

Chest X-ray

Large bilateral pulmonary cavities.

Large bilateral pulmonary cavities, the largest ones containing liquid forming fluid level.

Case Discussion

Granulomatosis with polyangitis (Wegener granulomatosis), is a multi-system systemic necrotizing non-caseating granulomatous vasculitis affecting small to medium-sized arteries, capillaries and veins, and the lungs are the most frequently involved organ, seen in 95% of cases.

The most common radiological presentation is with multiple nodules randomly distributed. In approximately half of cases, some of the nodules demonstrate cavitation, which is best seen with CT.

This case shows multiple cavities and the patient has recurrent pulmonary infections (caused by usual bacteria). On the last hospitalization she was submitted to thoracic drainage and subsequent surgical intervention.

Patient was confirmed to have Granulomatosis with polyangiitis (Wegener granulomatosis).

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Case information

rID: 26659
Published: 1st Jan 2014
Last edited: 16th Jul 2018
System: Chest
Inclusion in quiz mode: Included

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