Presentation
2 months increasing shortness of breath. Common variable immune defiency (CVID) with previous recurrent sinopulmonary infections.
Patient Data
Lower lobe and peribronchovascular predominance of solid and ground glass nodules. Mild airway dilatation and interlobular septal thickening is also present. There are associated enlarged mediastinal lymph nodes.
Case Discussion
This is a biopsy proven case of granulomatous-lymphocytic interstitial lung disease. The patient was commenced on Rituximab following the above CT, and demonstrated clinical and radiological improvement.
This case demonstrates several typical features for GLILD. Splenomegaly was also present on a CT Abdomen (not shown). This diagnosis, however, requires the exclusion of other causes, most importantly infection, but drug reaction and malignancy should also be considered.
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