Granulomatous prostatitis

Case contributed by Yu-Ming Tang
Diagnosis almost certain

Presentation

History bladder tumor. Post surgery, BCG and interferon. PSA 5. Rule out prostate carcinoma.

Patient Data

Age: 60 years
Gender: Male

Multiparametric MRI

mri

Focal highly suspicious lesion in the left posterior and posterolateral PZ base. Homogenous hypointense on T2WI. Broad-based capsular bulging raises the possibility of extracapsular invasion. Restricted diffusion with an ADC value of 550. Type 3 enhancement curve. Overall PIRADS score 5/5. 

Case Discussion

TRUS biopsy showed granulomatous prostatitis and no carcinoma.

Granulomatous prostatitis is a well described known mimicker of prostate carcinoma, clinically and on MRI.  Clinically it often presents with elevated PSA and a firm nodule on DRE. On MRI, the lesion demonstrates typical features of a highly suspicious neoplastic lesion.

Currently, histopathology is the only means of establishing the diagnosis and excluding a tumor.  

Possible causes include previous intravesical BCG treatment for bladder carcinoma, TB prostatitis, previous intervention (eg TURP) and idiopathic.

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