Presentation
Severe thyrotoxicosis and large goiter.
Patient Data
Age: 35 years
Gender: Female
From the case:
Graves disease
Axial C+ split bolus
Diffuse enlargement of the thyroid gland, with evidence of a pyramidal lobe. Mild narrowing of the trachea.
From the case:
Graves disease
Thyroid uptake scan
Diffuse increased tracer uptake within both lobes of an enlarged thyroid gland.
From the case:
Graves disease
Thyroid function tests and anti-thyroid antibodies
The TSH Receptor Ab (TRAB) is highly positive, consistent with Graves disease.
Case Discussion
Graves disease is an autoimmune disease characterized by hyperthyroidism triggered by thyroid-stimulating antibodies. Another differential diagnosis for an enlarged thyroid and circulating antibodies includes Hashimoto's thyroiditis. However, the presence of TSH receptor antibody (TRAb) is most consistent with Graves disease.