Haemangioblastoma

Case contributed by A.Prof Frank Gaillard

Presentation

Seizure

Patient Data

Age: 20 years
CT

Low attenuation and mass effect is present in the posteroinferior aspect of the left temporal lobe. 

MRI

A high T2, low T1, vividly enhancing mass abutting the tentorium on the left and invaginating into the posterior temporal lobe is present. It contains prominent flow voids appearing to arise from, or drain to, the dura near the transverse sinus. 

Case Discussion

The patient went on to have a resection.

Histology

MICROSCOPIC DESCRIPTION:

Paraffin sections show fragments of an intensely vascular, moderately hypercellular tumour with a meningeal attachment. Vascular spaces vary from large calibre thin-walled sinuses down to capillaries. The latter enclose lobules of cells with features consistent with stromal cells. No mitotic figures or areas of necrosis are identified.

Immunohistochemistry shows negative staining for EMA, inhibin, CD34, GFAP, CAM5.2, S-100, tyrosinase and ALK-1.

DIAGNOSIS: Haemangioblastoma (WHO grade I).

Discussion

This case exemplifies the difficulty in reconciling various factors (location, appearance, demographic) when appearances are unusual. It also highlights the fact that their pial origin makes a distinction between intra- vs extra-axial difficult. 

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Case information

rID: 48791
Case created: 24th Oct 2016
Last edited: 28th Feb 2017
Inclusion in quiz mode: Included

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