Hemangiopericytoma

Case contributed by Dr Bahman Rasuli

Presentation

Vertigo and headache.

Patient Data

Age: 55
Gender: Female
MRI

There is a 17*22 mm abnormal signal (iso on T1 and low onT2 sequences) solid, avid enhancing mass lesion at the anatomical region of the pineal gland and superior cerebellar cistern with pressure effect on the tectal plate.

Multiple and confluent high signal foci on T2 and FLAIR sequences in the subcortical and periventricular white matter of both cerebral hemispheres (Fazekaskas III) depict microvascular ischemic events.

VP shunt inserted to the trigone of right lateral ventricle with adjacent gliosis also is seen in the right cerebral hemisphere.

Case Discussion

A pathologically proven case of hemangiopericytoma.

Histopathology

A vascular neoplasm composed of mild atypical cells with vesicular nuclei, visible nucleoli, eosinophilic and focal clear cytoplasm and stag-horn like intratumoral blood vessels arranged in sheet-like feature. No necrosis is seen. Few mitotic figure(up to 3/10 HPF) are noted. Foci of eosinophilic collagenous bands are evident.

IHC study revealed:

  • CD34: Positive
  • CD117: Positive
  • CD99: Positive
  • Vimentin: Non specific
  • EMA: Negative
  • PR; Negative
  • S100: Negative
  • GFAP: Negative
  • Ki 67: Up to 2-3%
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Case information

rID: 62937
Published: 10th Sep 2018
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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