Hemophilia type A, a history of multiple recurrent hemarthroses.
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There are prominent osteoarthritic changes with severe narrowing of the articular fissures, especially in the patellofemoral joint.
Excessive hemosiderin deposits on the synovial layers.
Frequent recurrent hemarthroses lead to accumulation of the hemosiderin on the synovia, further, it'll damage the secretion of the synovial fluid, that, in turn, promotes early osteoarthritis.