Healing non-ossifying fibroma

Case contributed by Yaïr Glick
Diagnosis almost certain


Pain in proximal and distal calf. Denies history of trauma.

Patient Data

Age: 25 years
Gender: Male

Spindle-shaped, mildly expansile sclerotic lesion with sharp borders in the lateral aspect of the distal tibial metadiaphysis. No periosteal reaction.

Due to focal tenderness on palpation of the distal tibia, a bone scan was done.

Bone scan

Nuclear medicine

Mild radiotracer uptake in distal right tibia corresponding to the location of the lesion on plain film.

MRI of distal calf


Eccentric lesion in lateral aspect of distal tibial diametaphysis. Lesion has sharply demarcated lobulated border, expands cortex mildly but does not violate its border or cause periosteal reaction. Intermediate T1 signal intensity (SI) and very low T2 SI; no contrast enhancement.

At lower edge of scan, tiny structure in the tibiotalar joint, devoid of signal on all sequences - probably a loose body.

Case Discussion

As exemplified here, healing non-ossifying fibroma can exhibit mild radiotracer uptake on bone scan.

At MRI, it has low signal intensity on all sequences.

To complete the picture: Knee MRI (not included) showed a compression fracture of the posterolateral rim of the tibial plateau with adjacent bone marrow edema in the tibial epiphysis and lateral femoral condyle.

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