Diabetes mellitus. Ferritin >2000 ng/ml. Brownish complexion.
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Complete signal loss of the liver parenchyma in all sequences due to iron overlaod. The spleen is not affected (as would be the case in non-hereditary haemosiderosis)
HHT patients with ferritin levels >1000 ng/ml are at an increased risk of developing liver cirrhosis and hepatocellular carcinoma.