Heterotaxy Syndrome

Case contributed by Ayman Mustafa , 19 Sep 2022
Diagnosis certain
Changed by Jeremy Jones, 21 Sep 2022
Disclosures - updated 3 May 2022:
  • Radiopaedia Events Pty Ltd, Jeremy is a director of Radiopedia Events Pty Ltd (ongoing)

Updates to Case Attributes

Status changed from pending review to published (public).
Presentation was changed:
A 23-year-old female with a pastPast medical history of orthotopic heart transplantation for complex congenital heart disease complicated by chronic antibody-mediated rejection. Surgical history of distal pancreatectomy and right hemicolectomy.
Published At was set to .
Age changed from 23 to 25 years.

References changed:

  • Applegate K, Goske M, Pierce G, Murphy D. Situs Revisited: Imaging of the Heterotaxy Syndrome. Radiographics. 1999;19(4):837-52. <a href="https://doi.org/10.1148/radiographics.19.4.g99jl31837">doi:10.1148/radiographics.19.4.g99jl31837</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/10464794">Pubmed</a>
  • Ghosh S, Yarmish G, Godelman A, Haramati L, Spindola-Franco H. Anomalies of Visceroatrial Situs. AJR Am J Roentgenol. 2009;193(4):1107-17. <a href="https://doi.org/10.2214/ajr.09.2411">doi:10.2214/ajr.09.2411</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/19770335">Pubmed</a>
  • Applegate K, Anderson J, Klatte E. Intestinal Malrotation in Children: A Problem-Solving Approach to the Upper Gastrointestinal Series. Radiographics. 2006;26(5):1485-500. <a href="https://doi.org/10.1148/rg.265055167">doi:10.1148/rg.265055167</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/16973777">Pubmed</a>
  • Levine D, Barnewolt C, Mehta T, Trop I, Estroff J, Wong G. Fetal Thoracic Abnormalities: MR Imaging. Radiology. 2003;228(2):379-88. <a href="https://doi.org/10.1148/radiol.2282020604">doi:10.1148/radiol.2282020604</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/12821772">Pubmed</a>
  • Haramati L, Glickstein J, Issenberg H, Haramati N, Crooke G. MR Imaging and CT of Vascular Anomalies and Connections in Patients with Congenital Heart Disease: Significance in Surgical Planning. Radiographics. 2002;22(2):337-47; discussion 348. <a href="https://doi.org/10.1148/radiographics.22.2.g02mr09337">doi:10.1148/radiographics.22.2.g02mr09337</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/11896223">Pubmed</a>
  • Lane F. Donnelly. Pediatric Imaging. (2009) ISBN: 9781416059073 - <a href="http://books.google.com/books?vid=ISBN9781416059073">Google Books</a>
  • Shapiro A, Davis S, Ferkol T et al. Laterality Defects Other Than Situs Inversus Totalis in Primary Ciliary Dyskinesia. Chest. 2014;146(5):1176-86. <a href="https://doi.org/10.1378/chest.13-1704">doi:10.1378/chest.13-1704</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/24577564">Pubmed</a>
  • Kim S. Heterotaxy Syndrome. Korean Circ J. 2011;41(5):227. <a href="https://doi.org/10.4070/kcj.2011.41.5.227">doi:10.4070/kcj.2011.41.5.227</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/21731561">Pubmed</a>
  • 1. Applegate K, Goske M, Pierce G, Murphy D. Situs Revisited: Imaging of the Heterotaxy Syndrome. Radiographics. 1999;19(4):837-52; discussion 853-4. doi:10.1148/radiographics.19.4.g99jl31837  2. Ghosh S, Yarmish G, Godelman A, Haramati L, Spindola-Franco H. Anomalies of Visceroatrial Situs. AJR Am J Roentgenol. 2009;193(4):1107-17. doi:10.2214/AJR.09.2411  3. Applegate K, Anderson J, Klatte E. Intestinal Malrotation in Children: A Problem-Solving Approach to the Upper Gastrointestinal Series. Radiographics. 2006;26(5):1485-500. doi:10.1148/rg.265055167  4. Levine D, Barnewolt C, Mehta T, Trop I, Estroff J, Wong G. Fetal Thoracic Abnormalities: MR Imaging. Radiology. 2003;228(2):379-88. doi:10.1148/radiol.2282020604  5. Haramati LB, Glickstein JS, Issenberg HJ et-al. MR imaging and CT of vascular anomalies and connections in patients with congenital heart disease: significance in surgical planning. Radiographics. 22 (2): 337-47. 6. Donnelly L. Pediatric Imaging. (2009) ISBN: 9781416059073 7. Shapiro A, Davis S, Ferkol T et al. Laterality Defects Other Than Situs Inversus Totalis in Primary Ciliary Dyskinesia: Insights into Situs Ambiguus and Heterotaxy. Chest. 2014;146(5):1176-86. doi:10.1378/chest.13-1704  8. Kim S. Heterotaxy Syndrome. Korean Circ J. 2011;41(5):227-32. doi:10.4070/kcj.2011.41.5.227 

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