High grade ductal carcinoma in situ: MRI findings

Case contributed by Chris O'Donnell
Diagnosis almost certain

Presentation

Presents with blood-stained nipple discharge from left breast

Patient Data

Age: 40
Gender: Female

Extensive irregular calcification throughout the left breast without a discrete mass especially medially

Irregular mass on the inner aspect of the left breast with abnormal vascularity indicative of neoplasm

Diffuse abnormal enhancement within the left breast. It is relatively rapid and predominately plateau in configuration (green color) although there are foci of washout (red color) enhancement medially at the site of ultrasonic abnormality suggesting higher grade DCIS or even invasive ductal carcinoma. Note involvement of the entire breast including the nipple.

Case Discussion

MRI breast is useful to determine the extent of DCIS and also to decide if the pathology is bilateral. Lower grades of DCIS may not be visible on MRI (requires abnormal vascularity) thus it is important that mammography also be undertaken to detect the sometimes subtle areas of calcification associated with DCIS.

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