Hypersensitivity pneumonitis

Case contributed by Andrea Molinari
Diagnosis almost certain


Dyspnea on minimal exertion.

Patient Data

Age: 40 years
Gender: Female

Uniformly diffuse low-density ill-defined centrilobular micronodules.

Mosaic oligemia with air-trapping.

Calcified nodule in right lower lobe consistent with remote phlogosis.

Case Discussion

Hypersensitivity pneumonitis includes a group of diffuse granulomatous parenchymal lung diseases caused by sensitization to a broad variety of organic or inorganic low-molecular antigens.

Typical HRCT features encompass ground-glass opacities, mosaic attenuation, and ill-defined centrilobular nodules.

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