Hypoxic-ischemic brain injury in a full term infant
Delayed mental and motor milestones. History of severe birth asphyxia.
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Bilateral hyperintense signal are seen at basal ganglia, thalami and perirolandic cortex.
Severe asphyxia in term neonates result in injury involving the deep gray matter (putamina, ventrolateral thalami, hippocampi, dorsal brainstem, and lateral geniculate nuclei) and occasionally the perirolandic cortex.
These areas of the brain are actively myelinating (an energy-intensive process) or contain the highest concentrations of NMDA receptors at term and are, therefore, the most susceptible to neonatal hypoxic ischemic insult.
- 1.Huang BY, Castillo M. Hypoxic-ischemic brain injury: imaging findings from birth to adulthood. Radiographics : a review publication of the Radiological Society of North America, Inc. 28 (2): 417-39; quiz 617. doi:10.1148/rg.282075066 - Pubmed
- 2. Cabaj A, Bekiesińska-Figatowska M, Mądzik J. MRI patterns of hypoxic-ischemic brain injury in preterm and full term infants - classical and less common MR findings. Polish journal of radiology. 77 (3): 71-6. Pubmed