Ileocolic intussusception secondary to cecal adenocarcinoma

Case contributed by Dr Henry Knipe

Presentation

Severe right sided abdominal pain.

Patient Data

Age: 55 years
Gender: Female

Ileocolic intussusception (approximately 15 cm in length) with hyperenhancing wall thickening distally. Bowel wall and mesenteric vessels enhance normally. There is some fluid attenuation distally.

Small bowel is not dilated. Remainder of the colon appears unremarkable. Small volume of pelvic free fluid. No intraperitoneal free fluid. Small sliding hiatus hernia.

Case Discussion

The patient had a known history of a cecal tumor, and was awaiting surgery. Intussusception in older patients almost always has a pathological lead point. This patient proceeded to a right hemicolectomy. 

Histopathology

MACROSCOPIC DESCRIPTION:A right hemicolectomy with terminal ileum, large bowel, appendix, mesentery and omentum. Within the cecum, immediately adjacent to the appendiceal orifice and 35mm from the ileocecal valve is an ovoid rubbery brown tumor which invades 5mm deep into muscularis propria and is 2mm from the serosa which is shiny and smooth. The proximal 110mm of large bowel has edematous mucosa and a wall up to 10mm. The mesentery contains numerous rubbery tan lymph nodes up to 18mm. The omentum is unremarkable.

MICROSCOPIC DESCRIPTION: Sections of bowel show a moderately differentiated adenocarcinoma focally invading through muscularis propria into subserosa. Tumor comprises cribriform glands and nests of atypical columnar cells within fibrotic stroma. There is a prominent peritumoural Crohnoid lymphocytic infiltrate. Stromal clefting around tumor nests is present but lymphovascular and perineural invasion are not seen. Tumor is clear of serosa, margins and appendix. The cecum shows an area of marked submucosal edema, consistent with an area of intussusception. The omentum is unremarkable. There are twenty four lymph nodes with no evidence of malignancy.

DIAGNOSIS: Moderately differentiated adenocarcinoma, arising within cecum.

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Case information

rID: 49054
Published: 8th Nov 2016
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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