Inflammatory hepatic adenoma

Case contributed by Chris O'Donnell
Diagnosis almost certain

Presentation

Incidental finding on CT abdomen for epigastric abdominal pain.

Patient Data

Age: 20 years
Gender: Female

Incidental finding on CT

ct

Incidental vascular mass lesion in right hepatic lobe on the background of a very fatty liver (arrow)

Primovist MR contrast

mri

Markedly fatty liver with substantial loss of signal in the liver on the out of phase sequence as compared with the spleen.  Mass lesion in right hepatic lobe showing peripheral rim of T2 signal with slightly lower signal intensity to the central T2 signal increase.  Arterial phase enhancement with central core of absent enhancement persisting during the delayed phase (so-called atoll sign).

Follow-up MRI after 6 months

mri

Appearances are unchanged after 6 months (if anything the lesion is slightly smaller)

  • Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Case Discussion

There are 4 subtypes of hepatocellular adenoma: inflammatory hepatocellular adenoma, hepatocyte-nuclear-factor-1-alpha (HNF-1alpha-mutated) hepatocellular adenoma, beta-catenin-mutated hepatocellular adenomas and unclassified. 

The most common is the inflammatory subtype and is usually seen in young women with obesity, hepatic steatosis (as in this case), diabetes mellitus and alcohol abuse.  Classic appearance is T2 hyperintensity with delayed, persistent, peripheral contrast enhancement with an hepatocyte agent (Primovist) as in this case.  Differential diagnosis is focal nodular hyperplasia.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.