Infratentorial ependymoma

Case contributed by Dr Mohammad A. ElBeialy

Presentation

Chronic headache and sense of imbalance with unsteady gait.

Patient Data

Age: 35 years
Gender: Female
MRI

A large heterogeneous 4th ventricle mass lesion with mixed solid and cystic portions is seen filling the 4th ventricle and extending through the left lateral foramen of Luschka. The lesion shows heterogeneous predominantly isointense T1 and hyperintense T2 signal of its solid compartment. The cystic component shows heterogeneous, predominantly hypointense T1 and hyperintense T2 signal. Small foci of hypointensity on all pulse sequences are seen at the right inferior lateral aspect of the lesion that could be calcification. The lesion is seen measures 5 x 4.5 x 4 cm in its main axial and CC diameters, compressing the pons and left middle cerebellar peduncle. The lesion is seen compressing the 4th ventricle with moderate rather symmetrical hydrocephalus.

MR spectroscopy of the lesion shows elevated choline with depression of the neuronal markers; NAA and creatine as well as elevation of the lipid/lactate. 

No supra-tentorial mass lesion or parenchymal area of abnormal signal intensity. Partial empty sella. No sellar or juxta sellar masses. Normal cortical sulci. Mild bilateral maxillary sinusitis.

Case Discussion

Infratentorial 4th ventricle ependymoma (typical plastic tumor with extension through the outlet foramen) with moderate supratentorial hydrocephalic changes. Ependymoma has a peak in the 1-5 years old age group and a second peak in the mid-30s.

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Case information

rID: 23882
Case created: 16th Jul 2013
Last edited: 17th Dec 2015
Inclusion in quiz mode: Included

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