Intracardiac thrombus

Case contributed by Bruno Di Muzio
Diagnosis certain

Patient Data

Age: 40 years
Gender: Male

CT Chest

ct

There is a hypodense mass in the right atrium.

The lungs and pleural spaces are clear and the remainder of the study is unremarkable. 

Cardiac MRI

mri

Pedunculated right atrium mass with homogenous low signal. 

Macroscopy:  

  • Three pieces of pink/yellow tissue with focal muscle, 17mm- 25x15x8mm. 1RS of each on for frozen section. Frozen Section Diagnosis:  Cardiac muscle with overlying tissue with hemosiderin pigment. Differential thrombus vs myxoma. Await paraffin.
  • Labeled "Right atrial mass".  Multiple tan friable fragments of tissue, <1-50x35x20mm. The margins are ragged. The cut section reveals a firm variegated tan/yellow lesion with patchy hemorrhage but no necrosis. There is no normal myocardium or endocardium identified.

Microscopy: 

  • A. Sections show surface amorphous eosinophilic material deep to which there is collagenous matrix focally myxoid within which some spindled cells are seen admixed with scattered hemosiderin macrophage and present overlying myocardium with focal areas showing ingrowing blood vessels.
  • B. Sections consist predominantly of an amorphous eosinophilic material showing focal calcification

Diagnosis: 

  • A. Specimen base - organizing thrombus.
  • B. Right atrial mass - features in keeping with a calcified long-standing blood clot.

Case Discussion

Incidentally found right atrium intracardiac mass. Unfortunately, no postcontrast MRI images were obtained in this case, which would help in distinguishing the most common causes for such mass: myxoma vs. thrombus.

Further histology confirmed a long-standing intracardiac thrombus.   

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