Intraductal papilloma of breast

Case contributed by Dr Bruno Di Muzio


Nipple discharge on the left.

Patient Data

Age: 60-year-old
Gender: Female


Modality: Mammography

A surgical clip is noted in the medial right breast, with adjacent scarring. Moderately dense fibroglandular tissue. Scattered calcification is stable. No suspicious lesion, microcalcification or stromal distortion.


Modality: Ultrasound

The left nipple is retracted. Within the left breast, just medial to the nipple (9 o'clock) is a dilated duct containing an isoechoic lesion measuring 11mm in maximal dimensions demonstrating internal vascularity. It was non-compressible. No further lesions were identified within the vicinity of the nipple. This lesion was subsequently biopsied. No abnormal axillary lymph nodes.

Case Discussion

MICROSCOPIC DESCRIPTION: The sections show multiple cores of breast parenchyma which contains a papillary lesion. The papillary lesion is lined by a dual layer of epithelium. There is no evidence of in-situ or invasive malignancy.

DIAGNOSIS: Papillary lesion. Features in keeping with a papilloma.

As in this case, mammograms are frequently normal for intraductal papillomas, particularly the small ones. 

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Case Information

rID: 49325
Case created: 20th Nov 2016
Last edited: 29th Dec 2016
System: Breast
Tag: rmh
Inclusion in quiz mode: Included

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