Intraosseous haemophilic pseudotumor

Case contributed by Prashant Mudgal


Known case of hemophilia presented with pain and swelling in right knee

Patient Data

Age: 30 years
Gender: Male

There is a well-defined, slightly expansile, osteolytic lesion seen involving proximal right tibia. The lesion is surrounded by a thin sclerotic rim and displaying thin incomplete septa-like structures.

Lateral radiograph shows scalloping of the posterior margin of tibia (smaller arrows in the annotated image) and radiating trabeculae (larger arrow in the annotated image) mimicking a malignant or infectious periosteal reaction.

In a known case of hemophilia and considering the age of the patient, imaging features are most likely suggestive of an intraosseous haemophilic pseudotumor.

Case Discussion

Hemophilic pseudotumor is a rare complication occurring in 1–2% of patients with severe hemophilia.

Image differentials include:

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