Invasive solid papillary carcinoma of the breast

Case contributed by William Lee
Diagnosis certain


Family history of breast cancer in mother. Palpable, non-tender, mobile mass on examination. No inverted nipple, nipple discharge, skin changes, or tenderness.

Patient Data

Age: 80 years
Gender: Female

Bilateral craniocaudal and mediolateral oblique views from a digital screening mammogram demonstrate scattered areas of fibroglandular density in both breasts. In the central upper left breast, there is a well-circumscribed, oval, lobulated mass.

Left breast ultrasound at the 12:00 axis, 3 cm from the nipple, demonstrates an oval lobulated, heterogeneous mass measuring 2.0 x 2.3 x 1.7 cm.

Case Discussion

Papillary carcinoma of the breast is a histological subtype of breast cancer characterized by a micropapillary pattern and is associated with a favorable prognosis 1. Solid papillary carcinomas primarily present in postmenopausal patients as a palpable mass with or without nipple discharge 2.

Mammographically, papillary carcinoma of the breast presents as a well-circumscribed lesion in the shape of an oval or can be lobulated 3. Ultrasonography typically demonstrates either an anechoic or hypoechoic appearance, and invasive forms normally have an irregular shape.

In this particular case, surgical pathology report confirmed ER-positve, PR-positive, HER2-negative, invasive, solid papillary carcinoma.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.