Isolated hypoglossal nerve paralysis

Case contributed by Bahman Rasuli
Diagnosis almost certain

Presentation

Subtle deviation and decreased volume of the tongue on the right side from 18 months ago.

Patient Data

Age: 35 years
Gender: Male
This study is a stack
Coronal
T1
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Coronal T2
fat sat
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Axial
T1
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Axial T2
fat sat
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Axial
T2
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Axial T1
C+ fat sat
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Coronal T1
C+ fat sat
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Sagittal
T1 C+
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Axial
T1
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Axial
T2
This study is a stack
Axial
FLAIR
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Info

Affected right side of the tongue has a high signal on both T1WI and T2WI due to fatty infiltration as a consequence of longstanding denervation of the hypoglossal nerve.

Right hemiatrophy and deviation of the tongue to the right side.

Otherwise head and neck MRI is normal.

Case Discussion

Unilateral atrophy of the tongue is the most important radiologic feature of hypoglossal nerve paralysis. When it is identified, thorough assessment of the hypoglossal nerve from the brainstem to the tongue should be performed.

In acute hypoglossal nerve palsy:

  • tongue deviation toward the weak side
  • oedematous change (T1WI hypointense, T2WI hyperintense)

In chronic hypoglossal nerve palsy:

  • tongue deviation toward the weak side
  • tongue atrophy (volume loss)
  • fatty infiltration (both T1WI and T2WI hyperintense)

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