Labrune syndrome

Case contributed by Brendon Friesen
Diagnosis almost certain

Patient Data

Age: 50 years
Gender: Female

CT Brain

ct

Diffuse calcifications, cysts and leukoencephalopathy. Prior posterior fossa craniotomy and resection of a cyst.

Follow-up MRI brain

mri

Mutliple supratentorial enhancing cysts with susceptibiltiy artefact and some intrinsic T1 hyperintensity.

Diffuse white matter FLAIR hyperintensity.

Large right cerebellar cyst.

Case Discussion

This case illustrates a follow-up study in a patient with a known diagnosis of Labrune syndrome, which is a rare condition that consists of a triad of leukoencephalopathy, cerebral calcifications and cysts. 

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