Labrune syndrome

Case contributed by Brendon Friesen

Patient Data

Age: 50 years
Gender: Female

CT Brain


Diffuse calcifications, cysts and leukoencephalopathy. Prior posterior fossa craniotomy and resection of a cyst.

Follow-up MRI brain


Mutliple supratentorial enhancing cysts with susceptibiltiy artefact and some intrinsic T1 hyperintensity.

Diffuse white matter FLAIR hyperintensity.

Large right cerebellar cyst.

Case Discussion

This case illustrates a follow-up study in a patient with a known diagnosis of Labrune syndrome, which is a rare condition that consists of a triad of leukoencephalopathy, cerebral calcifications and cysts. 

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.