Labyrinthine schwannoma

Case contributed by Chris O'Donnell , 30 Dec 2016
Diagnosis almost certain
Changed by Andrew Murphy, 7 Jan 2017

Updates to Case Attributes

Age changed from 70 to 70 years.
Body was changed:

Most "acoustic" Schwannomas' schwannomas arise in the vestibular nerve at the vestibular ganglion that is at the junction of the central and peripheral myelin (in the fundus of the IAC). Schwannomas can actually occur anywhere along the canal where there are Schwann cells supporting peripheral myelin but can involve the membranous labyrinth i.e. cochlea, vestibule, or semicircular canals where there are also peripheral nerves.  These are known as labyrinthine Schwannomasschwannomas and are quirequite rare.

In this case, the very early finding of enhancement without mass effect in the modiolus and basal turn of the cochlea has been interpreted as an inflammatory process but over time the true tumourfactive nature of a Schwannomaschwannoma has been revealed.

  • -<p>Most "acoustic" Schwannomas arise in the vestibular nerve at the vestibular ganglion that is at the junction of the central and peripheral myelin (in the fundus of the IAC). Schwannomas can actually occur anywhere along the canal where there are Schwann cells supporting peripheral myelin but can involve the membranous labyrinth i.e. cochlea, vestibule, or semicircular canals where there are also peripheral nerves.  These are known as labyrinthine Schwannomas and are quire rare.</p><p>In this case the very early finding of enhancement without mass effect in the modiolus and basal turn of the cochlea has been interpreted as an inflammatory process but over time the true tumourfactive nature of a Schwannoma has been revealed.</p>
  • +<p>Most "acoustic' schwannomas arise in the vestibular nerve at the vestibular ganglion that is at the junction of the central and peripheral myelin (in the fundus of the IAC). Schwannomas can actually occur anywhere along the canal where there are Schwann cells supporting peripheral myelin but can involve the membranous labyrinth i.e. cochlea, vestibule, or semicircular canals where there are also peripheral nerves.  These are known as labyrinthine schwannomas and are quite rare.</p><p>In this case, the very early finding of enhancement without mass effect in the modiolus and basal turn of the cochlea has been interpreted as an inflammatory process but over time the true tumourfactive nature of a schwannoma has been revealed.</p>

References changed:

  • 1. Salzman KL, Childs AM, Davidson HC, Kennedy RJ, Shelton C, Harnsberger HR. Intralabyrinthine schwannomas: imaging diagnosis and classification. AJNR. American journal of neuroradiology. 33 (1): 104-9. <a href="https://doi.org/10.3174/ajnr.A2712">doi:10.3174/ajnr.A2712</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/22158921">Pubmed</a> <span class="ref_v4"></span>
  • Salzman KL, Childs AM, Davidson HC, Kennedy RJ, Shelton C, Harnsberger HR. Intralabyrinthine schwannomas: imaging diagnosis and classification. AJNR. American journal of neuroradiology. 33 (1): 104-9. <a href="https://doi.org/10.3174/ajnr.A2712">doi:10.3174/ajnr.A2712</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/22158921">Pubmed</a> <span class="ref_v4"></span>

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