Presentation
The patient presented with a persistent headache for 3 months.
Patient Data
Age: 14 years
Gender: Male
From the case:
Langerhans cell histiocytosis
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CT-scan found a nodular formation of soft tissues determining an osteolytic lesion (punched-out lytic lesion) in the left parietal bone.
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The lesion was surgically resected with subsequent cranioplasty.
Case Discussion
Langerhans cell histiocytosis is a rare multisystem disease with variable presentation, and it is more frequent in pediatrics.
A biopsy of the lesion confirmed the diagnosis of Langerhans cell histiocytosis histologically, demonstrating bone, meningeal, and soft tissue involvement. Immunohistochemistry identified the presence of the antibodies CD1a, S100, CD68, and CD5 in the sample. The lesion was surgically resected, followed by cranioplasty.
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