Langerhans cell histiocytosis (LCH)

Case contributed by Hani Makky Al Salam

Patient Data

Age: Child

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

A well defined lucent punched out skull lesions at the left frontal and parietal bones.

Multiple cervical, mediastinal, external iliac and inguinal lymph nodes. 

MDP bone scan

Nuclear medicine

Tc-99m-MDP bone scan AP image shows intense focus of radioisotope accumulation within the skull lesion. Incidental normal radioisotope uptake in epiphyseal plates in a skeletally immature patient is seen.

Case Discussion

Langerhans cell histiocytosis (LCH) with associated Hodgkin lymphoma.

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