Large skull metastasis from breast cancer

Case contributed by Dr Ammar Haouimi


Known for breast cancer, presented with a history of progressive painless swelling of the left parietal region.

Patient Data

Age: 45 years
Gender: Female

The MRI sequences demonstrate:

  • large soft tissue mass of the cranial vault centered on the left parietal region measuring 14 x 12 x 7 cm. It displays a low signal on T1, heterogeneous high signal on T2 and FLAIR with heterogeneous enhancement on postcontrast sequences. There is destruction of both inner and outer tables of the skull with extension to the adjacent segment of the superior sagittal sinus
  • multiple enhancing lesions of the cranial vault and left sphenoid wing are also noted (metastases)
  • irregular/nodular dural thickening with enhancement mainly along the left cerebral hemisphere (dural or pachymeningeal metastases)

Case Discussion

MRI features of pachymeningeal and skull metastases from breast cancer. The largest skull metastasis involves mainly the parietal bone with extension to the superior sagittal sinus.

In women, breast cancer is considered the most common primary malignancy of pachymeningeal and skull metastases.

PlayAdd to Share

Case information

rID: 90535
Published: 20th Jun 2021
Last edited: 21st Jun 2021
Inclusion in quiz mode: Included
Institution: Aurès Medical Imaging Center - Batna Algeria

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.