Left parietal lobe ganglioglioma (grade I)

Case contributed by Dr Andrei Tsoriev

Presentation

8-year-old girl with focal epilepsy.

Patient Data

Age: 8 years
Gender: Female

Well demarcated lobular mass in the cerebral cortex and juxtacortical white matter of left parietal lobe, it contains small cysts and thickened irregular cortex.

Annotated image

Focal mass with slightly elevated T2 and FLAIR signal, foci of restricted diffusion

Case Discussion

MRI detected mass-lesion in left parietal lobe, surgery was performed with radical resection of the tumor and pathological report statement was "ganglioglioma, WHO grade I".

In this case there is an unusual feature of the tumor - areas of restricted diffusion in otherwise benign tumor. There are cases in the literature, describing such phenomenon, attributing it to intermediate cellularity composed of ganglion cells and neoplastic astrocytes. That is why the presence of restricted diffusion itself should not lead to conclusion about malignancy of the tumor, and it is important to acknowledge, that high to intermediate cellularity can lead to restricted diffusion even in low grade benign tumors. 

PlayAdd to Share

Case information

rID: 55848
Case created: 27th Sep 2017
Last edited: 4th Nov 2017
Inclusion in quiz mode: Included
Institution: Ural State Medical University

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.