Leptomeneningeal carcinomatosis with moderate hydrocephalus and calvarial metastases
History of breast cancer post MRM and chemoradiotherpay. Now presenting with delirium and disturbed level of conciousness as well as vomiting and urine incontinence for 2 months.
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- diffuse leptomeningeal enhancement with hyperintense FLAIR signal seen smearing the cortical sulci as well as the basal cisterns.
- moderate supratentorial hydrocephalus with transependymal interstitial CSF permeation.
- altered marrow signal of the skull base and calvarial bones with hyointense T1 and T2 signal with heterogenous psot-contrast enhancment.
Leptomeningeal carcinomatosis and moderate hydrocephalus as well as calvarial matastases.
- Jung JM, Kim S, Joo J, Shin KH, Gwak HS, Lee SH. Incidence and risk factors for leptomeningeal carcinomatosis in breast cancer patients with parenchymal brain metastases. J Korean Neurosurg Soc. 2012 Sep;52(3):193-9. doi: 10.3340/jkns.2012.52.3.193. Epub 2012 Sep 30.