Leptomenigeal carcinomatosis - cauda equina

Case contributed by A.Prof Frank Gaillard

The cauda equina demonstrates extensive leptomeningeal thickening and enhancement in keeping with leptomeningeal carcinomatosis. 

Case Discussion

The patient had a history of lung cancer and went on to have large volume CSF. 


Cell block preparation of CSF

  1. Malignant cells present
  2. Strongly positive for pan-keratin on immunohistochemistry (and negative for CD20 and CD3)
  3. Diagnostic of metastatic non-small-cell carcinoma


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Case information

rID: 5415
Published: 19th Jan 2009
Last edited: 9th May 2016
Inclusion in quiz mode: Excluded

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