Leptomenigeal carcinomatosis - cauda equina

Case contributed by Assoc Prof Frank Gaillard

Lumbar spine


The cauda equina demonstrates extensive leptomeningeal thickening and enhancement in keeping with leptomeningeal carcinomatosis. 

Case Discussion

The patient had a history of lung cancer and went on to have large volume CSF. 


Cell block preparation of CSF

  1. Malignant cells present
  2. Strongly positive for pan-keratin on immunohistochemistry (and negative for CD20 and CD3)
  3. Diagnostic of metastatic non-small-cell carcinoma

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.