Leptomenigeal carcinomatosis - cauda equina
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The cauda equina demonstrates extensive leptomeningeal thickening and enhancement in keeping with leptomeningeal carcinomatosis.
The patient had a history of lung cancer and went on to have large volume CSF.
Cell block preparation of CSF
- Malignant cells present
- Strongly positive for pan-keratin on immunohistochemistry (and negative for CD20 and CD3)
- Diagnostic of metastatic non-small-cell carcinoma