Leptomenigeal carcinomatosis - cauda equina

Case contributed by Assoc Prof Frank Gaillard

Lumbar spine

The cauda equina demonstrates extensive leptomeningeal thickening and enhancement in keeping with leptomeningeal carcinomatosis. 

Case Discussion

The patient had a history of lung cancer and went on to have large volume CSF. 


Cell block preparation of CSF

  1. Malignant cells present
  2. Strongly positive for pan-keratin on immunohistochemistry (and negative for CD20 and CD3)
  3. Diagnostic of metastatic non-small-cell carcinoma


PlayAdd to Share

Case information

rID: 5415
Published: 19th Jan 2009
Last edited: 15th Oct 2019
Inclusion in quiz mode: Excluded

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.