Leukodystrophy: probable Canavan disease

Case contributed by Dr Vinay Shah


Global developmental delay.

Patient Data

Age: 12 months
Gender: Female

Diffuse hyperintense signal seen on the T2W images in the bilateral cerebral and cerebellar white matter. It involves almost majority of white matter in the bilateral cerebral and cerebellar hemisphere. 

Hyperintense signal is also seen on the T2W images involving the medulla, pons, brainstem, both thalami and both internal capsule. 

Case Discussion

These findings represents changes of leukodystrophy most likely to be Canavan disease

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Case information

rID: 19886
Published: 20th Oct 2012
Last edited: 14th Sep 2015
Inclusion in quiz mode: Included

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