Lhermitte-Duclos disease

Case contributed by Dr Ahmed Abdrabou


No neurological symptoms.

Patient Data

Age: 45 years
Gender: Female

Right cerebellar intra-axial lesion that displays striated appearance, iso to hypointense on T1 and hyperintense on T2 and FLAIR. There is no significant diffusion restriction or post-contrast enhancement.

MRS revealed mild choline elevation, yet normal NAA peak, in keeping with a benign nature. No lipids or lactate peak.

Case Discussion

This lesion was incidentally discovered 15 years previously. Comparison with the previous study (which was in hard copy) revealed no significant change in the appearance or pattern of this lesion which indicated a benign nature. It is most probably a hamartoma and the possibility of dysplastic cerebellar gangliocytoma is the most favourable diagnosis. Unfortunately, the patient refused undergo biopsy.

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Case information

rID: 65829
Published: 25th Jan 2019
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included
Institution: Ain Shams University

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