Lhermitte-Duclos disease

Case contributed by Dr Alexandra Stanislavsky

Presentation

3 week history of headaches.

Patient Data

Age: 38 years
Gender: Female

CT brain

Modality: CT

A large, heterogeneous, non enhancing and non-calcified right cerebellar mass compresses and distorts the fourth ventricle with resultant dilatation of the third and lateral ventricles and tonsillar herniation.There is no appreciable contrast enhancement following administration of contrast.

MRI brain

Modality: MRI

MRI confirms the abnormality. The mass is striated and hyperintense on T2 and grey matter isointense on T1, with no restricted diffusion and no contrast enhancement.

Case Discussion

This patient went on to have a posterior fossa craniotomy and biopsy, confiming the diagnosis of  Lhermitte-Duclos disease. Further investigations for possible Cowden syndrome did not demonstrate any hamartomatous lesions or tumours elsewhere.

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Case Information

rID: 10755
Case created: 18th Sep 2010
Last edited: 18th Dec 2015
Inclusion in quiz mode: Included

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