Lhermitte-Duclos disease

Case contributed by Dr Y. Amy Chen



Patient Data

Age: 25 years
Gender: Female

Predominantly nonenhancing hypodense mass in the right cerebellum causing mass effect on the posterior fossa structures, with effacement of the 4th ventricle.


MRI demonstrates a T1 hypointense T2 hyperintense nonenhancing lesion in the right cerebellum. T2-characteristics are classic, and show widened cerebellar folia with striated, "corduroy" appearance. The mass causes mass effect on the posterior fossa structures and effaces the 4th ventricle. There is no associated restricted diffusion nor increased perfusion.

Case Discussion

Lhermitte-Duclos (dysplastic gangliocytoma of the cerebellum) is a rare hamartomatous tumor of the cerebellum. It usually presents in young adults and is associated with Cowden's disease. MRI appearance is classic, with striated, "corduroy" appearance of widened cerebellar folia. 

PlayAdd to Share

Case information

rID: 51350
Published: 13th Feb 2017
Last edited: 13th Feb 2017
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.