Lipoid pneumonia

Case contributed by Dr Aneta Kecler-Pietrzyk


Increasing shortness of breath. Background history of colon adenocarcinoma.

Patient Data

Age: 50 years
Gender: Male

Frontal semierect chest radiograph demonstrating ill-defined opacities in the left hilum. 

Bibasal atelectasis. 

No pleural effusions. 

Repeat radiographs 7 and 14 days post treatment demonstrated no resolution of left hilar changes. 


Corresponding to the findings on chest radiograph there are ill-defined airspace opacity adjacent to the left hilum. 

Incidental note of cholelithiasis and a small hiatus hernia.

Case Discussion

Given patient's background and symptoms metastatic disease was of biggest concern and core biopsy was performed. Results of the histology as follows:

Left lung, core needle biopsy

Clinical details: 18 gauge core biopsy of left lung. Irregular mass like lesion. Background history right hemicolectomy for adenocarcinoma.

Gross description

Specimen container

Left lung core biopsy four cores of tissue ranging from 0.7 cm to 2 cm


Cores of lung parenchyma with a diffuse interstitial and intra-alveolar. Infiltrate of adipocytes and lipid-laden macrophages. A foreign body giant cell reaction is also present. There is no evidence of dysplasia or malignancy. The histological features are consistent with a lipoid pneumonia.

Lipoid pneumonia is a rare entity and mimics malignancy. It is often associated with aspiration as in this case (exogenous). Diagnosis is established with biopsy and histopathological analysis. 

PlayAdd to Share

Case information

rID: 62113
Published: 6th Aug 2018
Last edited: 14th Aug 2019
System: Chest
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.