Lithium nephropathy

Case contributed by Dr Charlie Chia-Tsong Hsu


68 year old female with bipolar affective disorder. On chronic lithium therapy.

Patient Data

Age: 65-70
Gender: Female

B mode ultrasound images of the kidneys demonstrate punctate echogenic foci located in both the renal medulla and cortex. The punctate echogenic appearance is attributed to microcysts (1-2 mm) with fibrotic margin and possible internal calcification. 

The patient has been on lithium therapy for her bipolar affective disorder for over 2 decades. There has been a progressive decline in renal function with current eGFR of 40 which prompted referral to renal physician and the ultrasound study.   

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Case information

rID: 19054
Published: 3rd Aug 2012
Last edited: 14th Aug 2019
System: Urogenital
Inclusion in quiz mode: Included

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