Localized pigmented villonodular synovitis

Case contributed by Dr Domenico Nicoletti


Knee pain without trauma. Incidental finding.

Patient Data

Age: 50 years
Gender: Female

MRI Left Knee without and with contrast

In the popliteal fossa, laterally, at the posterior surface of the femoral condyle in the gradient echo T2 sequences, is visible oval formation with blooming artifact caused by magnetic susceptibility from intracellular hemosiderin deposits.
This lesion, at regular margins, erodes the cortical plane of the femoral condyle and shows discrete enhancement after contrast.

Case Discussion

Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferative disease of the synovial membrane of joints, tendon sheaths, and bursas.

It presents in two forms: diffuse and localized.

The localized form is usually a single pedunculated mass or, less frequently, two or three nodules.

Histologically there is active proliferation of fibroblastic and histiocytic elements, showing macrophagic activity with phagocytosis of blood pigment (hemosiderin) and lipids.

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Case information

rID: 63223
Published: 20th Sep 2018
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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