Presentation
Recent right hemiarthroplasty, suspected periprosthetic fracture.
Patient Data
No evidence of fracture. No loosening of femoral stem.
Round soft-tissue lesion, hypodense to muscle, measuring 5.3 x 4.3 x 6.3 cm (LL x AP x CC), ballooning into the vastus intermedius from the anterior femoral cortex at the distal end of the femoral stem, eroding through the entire thickness of the cortex.
Total body 99mTc-MDP triphasic bone scintigraphy with pelvic SPECT:
- high-intensity horizontal uptake focus in the sacrum, compatible with fracture - osteoporotic insufficiency fracture? trauma?
- moderately increased uptake adjacent to the right hip prosthesis under the trochanter, with elevated early phase perfusion - clinical correlation required for ruling out infection
- increased irregular uptake in the shoulders and along the spine, degenerative arthritic changes in the knees
Mass measuring 7.3 x 4.5 x 4.9 cm with mixed echotexture in the front of the right hip, mostly hypoechoic with echogenic areas. The mass abuts the femoral bone.
Under local anesthesia with 7 ml of lidocaine 1%, four aspirations from the mass substance with 14G-18G needles. Transparent, whitish gelatinous substance received. Part of the material was placed on 8 slides for cytologic evaluation and part was transferred into a sterile stoppered syringe. In addition, two core biopsies were taken from the echogenic material with a Magnum device using a 14G needle. Two good-quality cores of the gelatinous/tissue material were obtained.
Intramedullary fixation in the proximal femoral diaphysis.
At the middle third of the thigh, deep inside the vastus intermedius, there is a lesion displaying a low signal on T1WI and a high signal on T2WI, that undergoes mild heterogeneous contrast enhancement. The lesion measures 4.8 x 4.7 x 8.1 cm (ml x ap x cc). It violates the cortex and reaches the tip of the intramedullary stem. The lesion's characteristics favor a soft-tissue sarcoma.
The neurovascular structures appear normal.
Case Discussion
Incidentally discovered soft-tissue lesion in the right thigh, eroding the femoral cortex. The lesion did not show increased uptake on bone scan. Ultrasound-guided biopsy and cytology obtained.
Pathology:
Soft tissue: (Right thigh Trucut) Cores of tumor composed of benign spindle cells without atypia and mitotic figures in a myxoid stroma.
Immunostains: Vimentin positive. Desmin negative. S100 negative. Smooth muscle actin negative. CD34 negative.
Findings probably of low-grade fibromyxoid sarcoma. For definite diagnosis, the entire lesion is needed for evaluation.