Lung metastases from uterine sarcoma

Case contributed by Bruno Di Muzio
Diagnosis almost certain


Patient with uterine leiomyosarcoma follow-up.

Patient Data

Age: 75 years
Gender: Female

Chest X-ray


Large pulmonary nodules distributed in the left lung.

CT Chest


Large pulmonary nodules distributed in the left lung.

Case Discussion

This case illustrates metastatic disease to the lungs. The abdomen and pelvis CT did not demonstrate para-aortic or intraperitoneal involvement. 

Uterine sarcoma metastasis ere demonstrated to most frequently involve the peritoneal cavity and omentum (~60%), followed by the lung (~50%), pelvic lymph nodes (~40%), para-aortic lymph nodes (38%), and liver parenchyma (34%) 1

The study showed also that the presence of lung metastasis was not associated with pelvic or para-aortic nodes metastasis or intraperitoneal disease. Metastasis to other distant sites including the brain, heart, kidney, and bone were independent of pelvic and para-aortic nodal metastasis or intraperitoneal disease 1.

Hematogenous metastasis best explains this metastatic pattern 1.

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