Macklin effect (illustrations)

Case contributed by Francisco Calle

Macklin Effect (Illustration)


Diagram depicting the pathology of Macklin effect.

Case Discussion

Macklin effect - key learning points:

  • increased alveolar pressure leads to rupture with passing of air into the pulmonary interstitium
  • the air dissects the peribronchovascular interstitium, interlobular septa and visceral pleura in a centripetal direction towards the hila
  • air finally reaches the mediastinum


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