Malignant spinal cord compression from glioblastoma drop metastasis
Severe back pain and gait disturbances in a patient who had been treated for cerebral glioblastoma multiforme 12 months earlier.
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There is a large intradural mass at the T3 level right to the spinal cord. The cord is displaced to the left and severely compressed. The mass is hyperintense on T2 and iso- to hypointense on T1 and enhances avidly. The T2-weighted images show extensive intramedullary oedema reaching from C4-T6. The contrast-enhanced images show a large intramedullary portion of the tumour.
Remote metastases in GBM may also spread along the vascular system but leptomeningeal drop metastases have been more freqently described in the literature1.