Marchiafava-Bignami disease

Case contributed by Dr Balint Botz


Known chronic alcohol abuse. Disorientated and somnolent.

Patient Data

Age: 50 years
Gender: Male

The entire corpus callosum is homogeneously hypodense. 

Case Discussion

With the history in mind the imaging appearance is pathognomonic for advanced Marchiafava-Bignami disease. Despite the prompt diagnosis and management in ICU the comatose state of the patient gradually worsened over the next few days and he eventually succumbed to the disease. 

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Case information

rID: 73702
Published: 19th Jan 2020
Last edited: 20th Jan 2020
Inclusion in quiz mode: Included
Institution: University of Pécs

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