Mature cystic ovarian teratoma

Case contributed by Adam Krajewski , 4 May 2020
Diagnosis certain
Changed by Mostafa Elfeky, 4 May 2020

Updates to Study Attributes

Modality changed from CT to Annotated image.

Updates to Freetext Attributes

Description was changed:

The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and appendectomy.

Histopathology

Keratinizing moderately differentiated squamous cell carcinoma arising in an ovarian cystic teratoma/dermoid cyst. Involvement of ovarian surface, fallopian tube surface, uterus, pelvic peritoneum and appendix.

Updates to Case Attributes

Body was changed:

Malignant transformation of ovarian teratomas occurs in 0.17-2% of cases1,3.

Squamous cell carcinoma, as seen in this case, is the most common type of histology seen in malignant degeneration (80% of reported cases)4.

  • -<p>• Malignant transformation of ovarian teratomas occurs in 0.17-2% of cases<sup>1,3</sup>.</p><p>• Squamous cell carcinoma, as seen in this case, is the most common type of histology seen in malignant degeneration (80% of reported cases)<sup><span style="font-size:10.8333px">4</span></sup>.</p>
  • +<p>Malignant transformation of ovarian teratomas occurs in 0.17-2% of cases <sup>1,3</sup>.</p><p>Squamous cell carcinoma, as seen in this case, is the most common type of histology seen in malignant degeneration (80% of reported cases) <sup>4</sup>.</p>

References changed:

  • 1. Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K. Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data. (2008) The Lancet. Oncology. 9 (12): 1173-80. <a href="https://doi.org/10.1016/S1470-2045(08)70306-1">doi:10.1016/S1470-2045(08)70306-1</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/19038764">Pubmed</a> <span class="ref_v4"></span>
  • 2. Comerci JT, Licciardi F, Bergh PA, Gregori C, Breen JL. Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. (1994) Obstetrics and gynecology. 84 (1): 22-8. <a href="https://www.ncbi.nlm.nih.gov/pubmed/8008317">Pubmed</a> <span class="ref_v4"></span>
  • 3. Outwater EK, Siegelman ES, Hunt JL. Ovarian teratomas: tumor types and imaging characteristics. (2001) Radiographics : a review publication of the Radiological Society of North America, Inc. 21 (2): 475-90. <a href="https://doi.org/10.1148/radiographics.21.2.g01mr09475">doi:10.1148/radiographics.21.2.g01mr09475</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/11259710">Pubmed</a> <span class="ref_v4"></span>
  • 4. Park SB, Kim JK, Kim KR, Cho KS. Imaging findings of complications and unusual manifestations of ovarian teratomas. (2008) Radiographics : a review publication of the Radiological Society of North America, Inc. 28 (4): 969-83. <a href="https://doi.org/10.1148/rg.284075069">doi:10.1148/rg.284075069</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/18635624">Pubmed</a> <span class="ref_v4"></span>
  • Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K. Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data. (2008) The Lancet. Oncology. 9 (12): 1173-80. <a href="https://doi.org/10.1016/S1470-2045(08)70306-1">doi:10.1016/S1470-2045(08)70306-1</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/19038764">Pubmed</a> <span class="ref_v4"></span>
  • Comerci JT, Licciardi F, Bergh PA, Gregori C, Breen JL. Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. (1994) Obstetrics and gynecology. 84 (1): 22-8. <a href="https://www.ncbi.nlm.nih.gov/pubmed/8008317">Pubmed</a> <span class="ref_v4"></span>
  • Outwater EK, Siegelman ES, Hunt JL. Ovarian teratomas: tumor types and imaging characteristics. (2001) Radiographics : a review publication of the Radiological Society of North America, Inc. 21 (2): 475-90. <a href="https://doi.org/10.1148/radiographics.21.2.g01mr09475">doi:10.1148/radiographics.21.2.g01mr09475</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/11259710">Pubmed</a> <span class="ref_v4"></span>
  • Park SB, Kim JK, Kim KR, Cho KS. Imaging findings of complications and unusual manifestations of ovarian teratomas. (2008) Radiographics : a review publication of the Radiological Society of North America, Inc. 28 (4): 969-83. <a href="https://doi.org/10.1148/rg.284075069">doi:10.1148/rg.284075069</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/18635624">Pubmed</a> <span class="ref_v4"></span>

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